What is Ozempic (Semaglutide)?

Ozempic is a medication containing semaglutide, a peptide-based GLP-1 receptor agonist, developed for the treatment of type 2 diabetes and now widely used for weight management and metabolic health as well.

Semiglutide works by mimicking the intestinal hormone GLP-1, which is responsible for regulating satiety, appetite, and blood sugar control. Through this mechanism, Ozempic effectively reduces hunger and promotes gradual, sustainable weight loss.

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Main effects of Ozempic (Semaglutide)

🍽 Appetite control
Semaglutide reduces hunger signals in the brain and slows gastric emptying, prolonging the feeling of fullness after meals.

🩸 Blood sugar control
Ozempic stimulates insulin secretion in response to meals and reduces glucagon release, helping to stabilize blood sugar levels, especially in the presence of insulin resistance.

⚖️ Weight loss
Thanks to reduced calorie intake and better appetite control, Semaglutide promotes fat loss without resorting to extreme diets.

🫀 Metabolic and cardiovascular support
The use of Ozempic is often associated with improvements in blood pressure, lipid profile, and inflammatory markers, reducing overall metabolic risk.

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How to take Ozempic (Semaglutide)

Semaglutide is supplied in a vial containing 2 mg of lyophilized powder and must be reconstituted with water for injections before use.
It is administered by weekly subcutaneous injection, always on the same day.

Indicative dosage schedule

• Weeks 1–4: 0.25 mg
• Weeks 5–8: 0.5 mg
• Weeks 9–12: 1.0 mg
• Week 13+: up to 2.0 mg (only if necessary and well tolerated)

It is not necessary to increase the dose if the current dose is already effective and well tolerated.

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Precautions and side effects

Possible side effects:

• Nausea (more common in the first few weeks)

• Reduced appetite

• Bloating or mild digestive discomfort

• Headache or fatigue

Main contraindications:

• Personal or family history of medullary thyroid carcinoma or MEN2 syndrome
• Pregnancy and breastfeeding
• Concomitant use with other GLP-1 agonists (e.g., tirzepatide, retatrutide)

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Storage

• Store in the refrigerator at 2–8 °C.

• Do not freeze

• Protect from light

• After reconstitution, use within approximately 30 days.